Greater Excitability in Social Brain Regions of Autistic Men Compared to Women

Summary: Males with autism have atypically enhanced excitation in the medial prefrontal cortex (mPFC). This area of the brain is associated with social cognition and self-reflection. Autistic women showed a more intact mPFC response, which was associated with a better ability to camouflage social difficulties in real-world settings.

August 4, 2020

Source: eLife

MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

Summary: TRIM family proteins play integral roles in the innate immune response to virus infection. MG53 (TRIM72) is essential for cell membrane repair and is believed to be a muscle-specific TRIM protein. Here we show human macrophages express MG53, and MG53 protein expression is reduced following virus infection.

17 July 2020

Source: Nature Communications

https://www.nature.com/articles/s41467-020-17177-6

Sniffing out smell: How the brain organizes information about odors

Summary: Neuroscientists describe for the first time how relationships between different odors are encoded in the brain. The findings suggest a mechanism that may explain why individuals have common but highly personalized experiences with smell, and inform efforts better understand how the brain transforms information about odor chemistry into the perception of smell.

July 2, 2020

Source: Harvard Medical School

https://www.sciencedaily.com/releases/2020/07/200702144119.htm